CV

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Work

• Research Associate, Imperial College London, 2023 - Present

Education

• PhD in Applied Mathematics, University of Leeds, 2023
• BSc in Mathematics, Pontificia Universidad Javeriana, 2018

Experience

• Secondments

  • St Jude Children’s Research Hospital (09/2019–11/2019, 06/2022)

• Workshops

  • SISMID, University of Washington, Seattle, USA
    • Pathogen Evolution, Selection, and Immunity
  • SISBID, University of Washington, Seattle, USA
    • Supervised Methods for Statistical Machine Learning
    • Visualization of Biomedical Big Data
  • Fundamentals of Deep Learning, NVidia Deep Learning Institute, UK
  • QuanTII Complementary Skill Workshop, University of Leeds, Leeds, UK
  • RNA-Seq workshop, University of Leeds, Leeds, UK

Computing Skills

Publications

Multi-variate model of T cell clonotype competition and homeostasis

Daniel Luque Duque, Jessica A Gaevert, Paul G Thomas, Martín López-García, Grant Lythe, and Carmen Molina-París. Multi-variate model of T cell clonotype competition and homeostasis. Scientific Reports, volume 13, page 21995. Nature Publishing Group UK London, 2023.

Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

Chun-Yang Lin, Joshua Wolf, David C Brice, Yilun Sun, Macauley Locke, Sean Cherry, Ashley H Castellaw, Marie Wehenkel, Jeremy Chase Crawford, Veronika I Zarnitsyna, Daniel Duque, Kim J. Allison, et al. Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response. Cell Host & Microbe, volume 30, pages 83–96.e4. Elsevier, 2022.

Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses

Jessica Ann Gaevert, Daniel Luque Duque, Grant Lythe, Carmen Molina-París, and Paul Glyndwr Thomas. Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses. Viruses, volume 13, page 1786. Multidisciplinary Digital Publishing Institute, 2021.

Stochastic modelling of the T cell repertoire with epitope affinity

Daniel F Luque Duque, Carmen Molina-Paris, Grant Lythe, Martin Lopez Garcia, Paul Glyndwr Thomas, and Jessica Gaevert. Stochastic modelling of the T cell repertoire with epitope affinity. The Journal of Immunology, volume 204, Supplement, pages 94.18–94.18, 05 2020.

Talks

Estimating T cell proliferation: Using maths to answer biological questions

March 17, 2026

Talk at Imperial College London, Better Bioinformatics seminar series, London, UK

Quantifying thymic output using TCR sequencing data

September 04, 2025

Poster at UK Mathematical Biology Conference 2025, Birmingham, UK

Quantifying thymic output using TCR sequencing data

May 27, 2025

Poster at Antwerp TCR meeting 2025, Antwerp, Belgium

Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity

September 20, 2022

Poster at 12th European Conference on Mathematical and Theoretical Biology, Heidelberg, Germany

Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity

June 29, 2022

Talk and Poster at Viral Immunity: Basic Mechanisms and Therapeutic Applications, Keystone Symposia, Keystone CO, USA

Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity

February 08, 2022

Talk at DSABNS2022, Basque Center for Applied Mathematics (online), Bilbao, Spain

Multivariate competition for survival stimulus of T cell clonotypes in homeostasis

November 28, 2021

Poster at BSI21, British Society for Immunology, Edinburgh, UK

Multi-variate competition for survival stimulus of T cell clonotypes in homeostasis

June 17, 2021

Talk at SMB21, Society for Mathematical Biology, University of California Riverside (Online), Riverside CA, USA

Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity

June 04, 2021

Poster at 5th Workshop on Virus Dynamics, Fred Hutchinson Cancer Research Center (Online), Seattle WA, USA

Stochastic modelling of T cell populations

April 16, 2021

Talk at Pontificia Unversidad Javeriana, Department of Mathematics (Online), Bogotá, Colombia

Teaching

Introduction to Mathematical modelling in Immunology

MATH2920 Computational Mathematics