Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses
Gaevert, J. A., Luque Duque, D., Lythe, G., Molina-París, C., & Thomas, P. G. (2021). Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses. Viruses, 13(9), 1786.
CV
Education
- BSc in Mathematics, Pontificia Universidad Javeriana, 2018
- PhD in Applied Mathematics, University of Leeds, 2022 (expected)
Experience
Secondments
- St Jude Children’s Research Hospital (09/2019–11/2019, 06/2022)
Workshops
- SISMID, University of Washington, Seattle, USA
- Pathogen Evolution, Selection, and Immunity
- SISBID, University of Washington, Seattle, USA
- Supervised Methods for Statistical Machine Learning
- Visualization of Biomedical Big Data
- Fundamentals of Deep Learning, NVidia Deep Learning Institute, UK
- QuanTII Complementary Skill Workshop, University of Leeds, Leeds, UK
- RNA-Seq workshop, University of Leeds, Leeds, UK
- SISMID, University of Washington, Seattle, USA
Computing Skills
| General | Programming languages |
|---|---|
| Git | Python |
| GitHub | Mathematica |
| LaTeX | C++ |
Publications
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response
Chun-Yang Lin, Joshua Wolf, David C Brice, Yilun Sun, Macauley Locke, Sean Cherry, Ashley H Castellaw, Marie Wehenkel, Jeremy Chase Crawford, Veronika I Zarnitsyna, Daniel Duque, Kim J. Allison, et al. Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response. Cell Host & Microbe, volume 30, pages 83–96.e4. Elsevier, 2022.
Multi-variate model of T cell clonotype competition and homeostasis
Daniel Luque Duque, Martín López García, Jessica A. Gaevert, Grant Lythe, Paul G. Thomas, and Carmen Molina-París. Multi-variate model of T cell clonotype competition and homeostasis. Submitted to: Scientific Reports, 2022
Talks
Stochastic modelling of T cell populations
Talk at Pontificia Unversidad Javeriana, Department of Mathematics (Online), Bogotá, Colombia
Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity
Poster at 5th Workshop on Virus Dynamics, Fred Hutchinson Cancer Research Center (Online), Seattle WA, USA
Multi-variate competition for survival stimulus of T cell clonotypes in homeostasis
Talk at SMB21, Society for Mathematical Biology, University of California Riverside (Online), Riverside CA, USA
Multivariate competition for survival stimulus of T cell clonotypes in homeostasis
Poster at BSI21, British Society for Immunology, Edinburgh, UK
Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity
Talk at DSABNS2022, Basque Center for Applied Mathematics (online), Bilbao, Spain
Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity
Talk and poster at Viral Immunity: Basic Mechanisms and Therapeutic Applications, Keystone Symposia, Keystone CO, USA
Stochastic modelling of TCR-epitope recognition in the context of cross-reactivity
Poster at 12th European Conference on Mathematical and Theoretical Biology, Heidelberg, Germany